MOLECULAR DIAGNOSTIC LAB

http://pathology.wustl.edu/patientcare/moldiagnostic.php

Director:	Jacquline E. Payton, M.D., Ph.D., Lab Director Instructor, Division of Laboratory and Genomic Medicine Office: 314-362-5935 jpayton@path.wustl.edu
Technical Supervisor:			Agnes Austria 314-454-7601; FAX 454-8485 Axa7966@bjc.org
Location:		BJH North Campus, 216 S. Kingshighway Room 2320 454-8685; 9 AM – 5 PM Mon-Fri
Test Menu:		Direct mutation detection for inherited genetic and molecular pathology disorders including: Fragile X Syndrome, FXTAS, Cystic Fibrosis, LCHAD and MCAD deficiencies, Prader-Willi/Angelmen Syndrome (PWS-AS), Beckwith-Wiedemann Syndrome(BWS), Factor V Leiden, Prothrombin gene mutation, MEN2A/FMTC, MEN2B; hematopathology testing including BCR-ABL, PML-RAR alpha, BCL2, FLT3, JAK2, Hematopoietic stem cell engraftment studies, IgH and TCR gamma gene rearrangements, IGJH somatic hypermutation, Thymidylate synthase enhancer mutation, UGT1A1 mutation detection (currently done as research), Warfarin Sensitivity (CYP2C9 and VKORC1), and hTERC Dyskeratosis Congenita.
		Saromas Alveolar Rhabdomyosarcoma, Ewings/PNET Sarcoma, DSRCT-Desmoplastic small round cell tumor and Snyovial Sarcoma detected by fusion gene message and direct DNA sequencing.
MDL Request Form must accompany all specimens.
Face sheet with patient demographics required for billing information.
Tests require lavender top EDTA peripheral blood specimens.
Bone marrow specimens also accepted when appropriately anticoagulated.
Skin or lymph node biopsies (fresh, frozen or paraffin embedded) and buccal swabs also accepted.
Test reports are posted directly in Clincal Desktop and mailed directly to requesting physician.
For information regarding specimen requirements, results, and test interpretation please call 454-8685 or 454-7601 or view website (listed above).