DRUG SCREEN, COMPREHENSIVE

Combination of Colorimetric/Immunoassay/Thin-Layer

Chromatography (TLC) for Screening

Confirmation tests depend on the drug being confirmed; gas chromatography, gas chromatography/mass spectrometry (GC/MS), immunoassay, or TLC may be performed.

NOTE:

Qualitative analysis is performed on gastric fluid and urine specimens with select quantitation in the serum. All positive qualitative results will be analyzed by 2 methods before being reported as detected.

 

Test Performed At:

 

 

Barnes-Jewish Hospital Laboratory

 

Specimen Required:

 

 

Both blood and urine or gastric fluids are required for this test.

 

 

 

 

Blood

 

 

Draw 5.0 mL blood in red-top tube(s).  (Green-top (lithium heparin) tubes WITHOUT Separator may be used but is NOT preferred sample).  SST® GEL-TUBE IS NOT ACCEPTABLE. 

 

 

NOTE:

1.

A Betadine® wipe must be used to cleanse the skin.

 

 

 

2.

Do not use alcohol wipes for venipuncture.

 

 

 

3.

Label specimen appropriately (blood).

 

 

 

SUBMIT ONLY 1 OF THE FOLLOWING SPECIMENS:

 

 

 

 

Gastric Fluid

 

 

50 mL of gastric fluid.

 

 

NOTE:

Label specimen appropriately (gastric fluid).

 

 

 

 

Urine

 

 

50 mL (15 mL is the pediatric absolute minimum, will not allow for any confirmation testing) from a random urine collection in a urine container supplied by St. Louis Children’s Hospital. No preservative.  Send specimen refrigerated.

 

 

NOTE:

Label specimen appropriately (urine).

 

Laboratory Notes:

 

 

DO NOT SPIN.  Send whole blood to BJS with urine or gastric fluid.  If unable to obtain blood may send urine or gastric fluid without blood.  Serum is only used to quantify positive levels.

 

Reference Values:

 

 

None detected

 

 

Benzodiazepines and phenothiazine metabolites are reported as a class only.

 

 

 

 

 

 

See special instruction section for “Drugs Detectable by Drug Screens and Panels” for drugs detected and their sensitivity levels.

 

 

 

 

 

 

The following drugs are automatically quantitated in the blood if present in gastric fluid and/or urine: acetaminophen, acetone, amobarbital, butabarbital, butalbital, carbamazepine, chlordiazepoxide, diazepam, ethanol, ethchlorvynol, glutethimide, isopropanol, methanol, nordiazepam, pentobarbital, phenobarbital, phenytoin, quinidine, salicylate, and secobarbital.

 

 

 

 

 

 

If a specimen is positive for any drug by the screening method, a confirmation will be ordered automatically.

 

Day(s) Test Set Up:

 

 

As received.

 

Cut-Off Time:

 

 

 

 

Turn Around Time:

 

 

Same day (TAT 4 hours not including confirmation testing)

 

CPT Code:

 

 

80100 x 3 -

drug screen; multiple drug  classes, each procedure

 

 

80101 x 6 -

drug screen; single drug  classes, each procedure

 

 

80102 -

drug confirmation; each procedure

 

Care Manager Order Name:

 

 

Comprehensive Drug Screen ONCE RTN

 

KIDDOS Order Name:

 

 

Comprehensive Drug Screen

 

Cerner Order Name:

 

 

Drug Scrn Comp

 

Last Updated 01/08