ALDOSTERONE, URINE

Reporting Title: Aldosterone, U

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

 

Test Performed At:

 

 

Mayo Medical Laboratories   #8556

 

Specimen Required:

 

 

Submit an entire 24-hour urine collection in a urine container supplied by St. Louis Children’s Hospital. Refrigerate specimen during collection, and send specimen refrigerated.   Call 314-454-4161 to obtain container.

 

 

NOTE:

INCLUDE COLLECTION START AND STOP TIME ON SPECIMEN CONTAINER.

 

Laboratory Notes:

 

 

Add 25 mL of 50% acetic acid as preservative at start of collection or within 4 hours of completion of collection (use 15 mL of 50% acetic acid for children <5 years old).  This preservative is intended to achieve a pH of between approximately 2.0 and 4.0. See special instructions for “Urine Preservatives” for multiple collections and special instructions “Renin — Aldosterone Studies” for detailed instructions.  Aliquot 11.0 mL (minimum 6.0 mL) from a 24-hour urine collection into a plastic, 13-mL urine tube (or 60-mL urine bottle). Send specimen refrigerated.

 

 

NOTE:

24-HOUR VOLUME IS REQUIRED ON REQUEST FORM FOR PROCESSING.

 

 

 

Urine Preservative Collection Options

 

 

IMPORTANT NOTE: 

The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

 

 

 

 

 

Ambient

Yes

 

 

 

Refrigerated

Yes

 

 

 

Frozen

Yes

 

 

 

6N HCl

No

 

 

 

50% Acetic Acid

Preferred

 

 

 

Na2CO3

No

 

 

 

Toluene Yes

Yes

 

 

 

6N HNO3

No

 

 

 

Boric Acid Yes

Yes

 

 

 

Thymol

Yes

 

 

 

 

 

 

Reference Values:

 

 

0-30 days:

0.7-11.0 mcg/24 hours*

 

 

1-11 months:

0.7-22.0 mcg/24 hours*

 

 

³1 year:

2.0-20.0 mcg/24 hours

 

 

NOTE:

*Loeuille GA. Racadot A, Vasseur P, Vandewalle B: Blood and urinary aldosterone levels in normal neonates, infants and children. Pediatrie 1981; 36:335-344.

 

 

 

Assay performed using analyte-specific reagent. See policies section, “Analyte-Specific Reagents (ASR) — Mayo Medical Laboratories.”

 

Day(s) Test Set Up:

 

 

Monday, Wednesday, Thursday; 3:00 p.m.

 

Cut-Off Time:

 

 

 

 

Turn Around Time:

 

 

4-8 days

 

CPT Code:

 

 

82088

 

Care Manager Order Name:

 

 

Aldosterone, 24 Hour Urine Battery ONCE RTN

 

KIDDOS Order Name:

 

 

Aldosterone 24 Hour Urine  Battery

 

Cerner Order Name:

 

 

24H Ur  Aldosterone SLC

 

Last Updated 07/09